- suppressor mutation
Mutation that alleviates the effect of a primary mutation at a different locus. May be through almost any mechanism that can give a primary mutation, but perhaps the most interesting class are the amber and ochre supressors, where the anticodon of the tRNA is altered so that it misreads the termination codon and inserts an amino acid, preventing premature termination of the peptide chain.
Dictionary of molecular biology. 2004.
Look at other dictionaries:
suppressor mutation — suppressor mutation. См. супрессорная мутация. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
suppressor mutation — noun (biology) A base change which suppresses the effect of mutations elsewhere • • • Main Entry: ↑suppress … Useful english dictionary
Suppressor mutation — A suppressor mutation is a mutation that counteracts the phenotypic effects of another mutation, by intra or extragenic (intergenic) mutation.External links* [http://en.wikibooks.org/wiki/General Biology/Genetics/Mutation#Mutation The mutations… … Wikipedia
suppressor mutation — a mutation that partially or completely masks phenotypic expression of another (primary) mutation but occurs at a different site from it (i.e., causes suppression); it may be intragenic or intergenic. The term is used particularly to describe a… … Medical dictionary
suppressor mutation — A mutation that reverses the effect of an earlier mutation, e.g. a mutation in a gene for a tRNA that permits it to read and override an amber mutation … Glossary of Biotechnology
suppressor mutation — A mutation that overcomes the effect of another mutation and produces the normal phenotype … Dictionary of microbiology
suppressor factor — (1) Factors released by T suppressor cells. (2) See suppressor mutation and ochre suppressor, opal suppressor … Dictionary of molecular biology
Mutation — A permanent change, a structural alteration, in the DNA or RNA. In humans and many other organisms, mutations occur in DNA. However, in retroviruses like HIV, mutations occur in RNA which is the genetic material of retroviruses. In most cases,… … Medical dictionary
suppressor — A compound that suppresses the effects of mutation or suppresses what would be a normal course of events. amber s. a mutant gene that codes for a tRNA whose anticodon has been altered so that the altered tRNA responds to UAG codons as well. * * * … Medical dictionary
suppressor gene — a gene that prevents the expression of another (non allelic) gene. * * * a gene that by its presence can reverse the effects of a specific mutation in another gene; see suppression (def. 3) … Medical dictionary